Physical Sciences → Chemistry → Organic Chemistry
Synthesis and biological activity
This cluster of papers focuses on the synthesis, biological activities, and therapeutic potential of heterocyclic compounds, particularly in the context of drug discovery. The research covers a wide range of applications, including the development of anticancer agents, tubulin inhibitors, vascular targeting agents, and anti-inflammatory/antioxidant compounds.
98.9K works worldwide922.4K citations
Heterocyclic CompoundsMedicinal ChemistryAnticancer AgentsTubulin InhibitorsVascular Targeting AgentsChalconesCoumarinsPyrazolesThiazolesBenzimidazoles
Journals publishing in this area
Articles on Scinovex in this research area
47 articles, most cited first
- Synthesis and anti-tubercular activity evaluation of hydrazide-hydrazone derivativesInternational Journal of Advanced Chemistry Research · 2025 · 1 citations · AI summary
- In silico characterization, homology modelling and structure-based functional annotation of Labeo rohita TLR4 proteinInternational Journal of Advanced Biochemistry Research · 2024 · 1 citations · AI summary
- Microwave assisted organic synthesis of nitrogen, oxygen and sulphur containing heterocyclesInternational Journal of Advanced Chemistry Research · 2023 · 1 citations · AI summary
- Comprehensive Review on: Chemistry and Biological Potential of 2- AzetidinoneInternational Journal of Advanced Chemistry Research · 2026 · 0 citations · AI summary
- Synthesis, docking studies, and in vitro antimicrobial and anticancer assessment of Mannich derivativesInternational Journal of Advanced Chemistry Research · 2026 · 0 citations · AI summary
- Preparation and characterization of triamterene complex with Diethyl 1-chlorohydrazine-1, 2-dicarboxylateInternational Journal of Advanced Chemistry Research · 2026 · 0 citations · AI summary
- QSAR-based evaluation of novel heterocyclic compounds as potential anticancer agentsInternational Journal of Advanced Chemistry Research · 2026 · 0 citations · AI summary
- Design, synthesis, molecular docking, and ADMET evaluation of heterocyclic compounds as anticancer and antibacterial agentsInternational Journal of Advanced Chemistry Research · 2026 · 0 citations · AI summary
- Pyrrolidine-mediated prodrug strategy for ibuprofen: Synthesis, characterization and biological evaluationInternational Journal of Advanced Chemistry Research · 2026 · 0 citations · AI summary
- Schiff base metal complexes as potential anticancer agents: Biological evaluation, and in silico studiesInternational Journal of Advanced Chemistry Research · 2026 · 0 citations · AI summary
- Apoptosis and ROS assessment of a 2-thioxoimidazolidin-4-one analogue using HepG2 cellsInternational Journal of Advanced Biochemistry Research · 2025 · 0 citations
- Design and synthesis of novel chalcone-aminoalkyl hybrids and evaluation of their antibacterial activityInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Discovery of chromen-2-one based hybrid molecules as potential anti-tubercular agents and their docking for MTBInternational Journal of Advanced Chemistry Research · 2025 · 0 citations
- Rational design of chalcone and pyrazole analogues inspired by curcumin: Synthesis and biological assessmentInternational Journal of Advanced Chemistry Research · 2025 · 0 citations
- Design, synthesis and antimicrobial activity of amide derivatives of pyrimidine-piperidine hybridsInternational Journal of Advanced Chemistry Research · 2025 · 0 citations
- Synthesis and docking-based evaluation of mannich derivatives targeting estrogen receptors in mcf-7 cells and evaluation of antibacterial activityInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Cytotoxic activity and Molecular docking studies of chalcone linked Isatin derivativesInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Bridging molecular design and global health equity: A critical review of quinolone-heterocycle hybrids as next-generation antimicrobialsInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Microwave-assisted synthesis and characterization of bioactive Benzimidazole-Oxadiazole HybridsInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Applicability of Deep Eutectic Solvent as a Sustainable Reaction Medium in Biocatalytic Multicomponent SynthesisInternational Journal of Advanced Chemistry Research · 2025 · 0 citations
- Synthesis and structure-activity relationships of isoxazole-based anti-inflammatory agentsInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Synthesis of benzothiophene sulfonamide derivatives as carbonic anhydrase inhibitorsInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Mechanochemical grinding synthesis of chalcone derivatives without solventInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Solvent-free synthesis of pyrazoline derivatives using grinding techniqueInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Molecular docking and ADMET prediction of novel thiazolidinedione derivatives as PPAR-γ agonistsInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Synthesis and evaluation of curcumin analogues as dual COX-2/5-LOX inhibitorsInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Synthesis and anticonvulsant activity of novel 1,3,4-oxadiazole derivativesInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- In silico ADMET prediction and pharmacokinetic profiling of benzoxazole anticancer candidatesInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Bioisosteric replacement strategy in the development of novel analgesic compoundsInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Novel azo dyes derived from 4-aminoantipyrine: Synthesis, spectral and biological evaluationInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Microwave-assisted one-pot synthesis of benzimidazole derivatives with enhanced bioactivityInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Synthesis and anticonvulsant activity of novel 1,3,4-oxadiazole derivativesInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Copper-catalysed synthesis of 2-substituted benzimidazoles under microwave conditionsInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Synthesis and biological evaluation of transition metal complexes of thiosemicarbazone schiff basesInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Ultrasound-assisted synthesis and antioxidant evaluation of novel thiazole derivativesInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Synthesis of chromene derivatives via knoevenagel condensation and their anticancer screeningInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Design, synthesis and molecular docking research of novel thiazolidinedione antidiabetic agentsInternational Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
- Synthesis, antibacterial and in silico study of 1, 3, 4 oxadiazole, triazole compounds derived from paracetamolInternational Journal of Advanced Chemistry Research · 2024 · 0 citations · AI summary
- Design and synthesis of some novel 1, 3, 5-trisubstituted pyrazolines derivatives for antimicrobial activitiesInternational Journal of Advanced Chemistry Research · 2024 · 0 citations · AI summary
- Synthesis of some novel benzimidazole derivatives act as antibreast cancer activityInternational Journal of Advanced Chemistry Research · 2024 · 0 citations · AI summary
- Biochemical evaluation of novel antibacterial compoundsInternational Journal of Advanced Biochemistry Research · 2024 · 0 citations
- Molecular docking and ADMET profiling of flavonoid derivatives as potential inhibitors of cyclooxygenase-2 enzymeInternational Journal of Advanced Chemistry Research · 2024 · 0 citations · AI summary
- Synthesis and characterization of some new Sulfamethoxazole derivativesInternational Journal of Advanced Chemistry Research · 2023 · 0 citations · AI summary
- Cytotoxic activity, corrosion inhibition activity and molecular docking studies of Imidazolone scaffolds-A reviewInternational Journal of Advanced Chemistry Research · 2021 · 0 citations · AI summary
- Synthesis of 6-aryl-7-arylazo-4-(N-substituted aminomethyl)-2H-thiazolo-[3, 2-a]-1, 3, 5-triazino-2-thiones as Antiviral AgentsInternational Journal of Advanced Biochemistry Research · 2020 · 0 citations · AI summary
- A mini review diverse biological activities of heterocyclic indole analoguesInternational Journal of Advanced Chemistry Research · 2019 · 0 citations
- A Kinetic approach to oxidation of p methoxy-benzaldehyde di-nbutyl acetal by n-chloroisonicotinamide in aqueous acetonitrile acid medium: A comprehensive and mechanistic studyInternational Journal of Advanced Chemistry Research · 2019 · 0 citations · AI summary

