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Health Sciences → Medicine → Pharmacology

Cholinesterase and Neurodegenerative Diseases

This cluster of papers focuses on the pharmacology and toxicology of cholinesterase inhibitors, particularly acetylcholinesterase and butyrylcholinesterase, in the context of neurodegenerative diseases such as Alzheimer's. It explores the development of multi-target-directed ligands, novel drug therapies, and the implications for cognitive deficits. The research also delves into the structure, function, and regulation of cholinesterases, as well as their potential roles in neuroprotection and neurorestoration.

53.6K works worldwide1M citations
Cholinesterase InhibitorsAcetylcholinesteraseButyrylcholinesteraseAlzheimer's DiseaseNeurodegenerative DiseasesMulti-Target-Directed LigandsPharmacologyToxicologyDrug DevelopmentCognitive Deficits

Journals publishing in this area

Articles on Scinovex in this research area

11 articles, most cited first

  1. Structure-based design of DYRK1A inhibitors for Alzheimer’s disease
    International Journal of Advanced Biochemistry Research · 2026 · 0 citations
  2. Drosophila as a cutting-edge platform for plant-based antioxidants in oxidative stress treatment
    International Journal of Biology Sciences · 2025 · 0 citations · AI summary
  3. Amyloid-beta peptide aggregation mechanisms, oligomer toxicity, and development of aggregation inhibitors as therapeutic agents
    International Journal of Advanced Biochemistry Research · 2025 · 0 citations
  4. In vitro investigation of inhibition kinetics and mechanism of acetylcholinesterase by natural bioactive compounds isolated from medicinal plants
    International Journal of Advanced Biochemistry Research · 2025 · 0 citations
  5. Synthesis of benzothiophene sulfonamide derivatives as carbonic anhydrase inhibitors
    International Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
  6. Computational identification of natural product-based inhibitors of acetylcholinesterase
    International Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
  7. Chemical composition and neuroprotective potential of Bacopa monnieri alkaloids
    International Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
  8. Enzyme kinetics and inhibition studies of human acetylcholinesterase by natural alkaloids
    International Journal of Biology Sciences · 2025 · 0 citations
  9. Alzheimer’s disease: Pathogenesis, diagnosis, and therapeutic strategies
    International Journal of Biology Sciences · 2024 · 0 citations · AI summary
  10. Understanding the biochemical basis of Alzheimer's disease: A clinical chemistry approach
    International Journal of Advanced Chemistry Research · 2024 · 0 citations · AI summary
  11. Biochemical signature in Alzheimer’s disease
    International Journal of Advanced Biochemistry Research · 2017 · 0 citations · AI summary