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Physical Sciences → Chemistry → Organic Chemistry

Click Chemistry and Applications

This cluster of papers focuses on the application of click chemistry, particularly the copper-catalyzed azide-alkyne cycloaddition, in chemical biology and drug development. It explores diverse chemical functionality, bioorthogonal chemistry, protein labeling, in vivo imaging, triazole synthesis, and the development of enzyme inhibitors.

51.8K works worldwide1.1M citations
Click ChemistryCopper-Catalyzed CycloadditionBioorthogonal ChemistryAzides and AlkynesChemical FunctionalityDrug DiscoveryProtein LabelingIn Vivo ImagingTriazole SynthesisEnzyme Inhibitors

Journals publishing in this area

1Angewandte Chemie International Edition cover
Angewandte Chemie International Edition
ISSN 1433-78512,381 articles in this topic
723h-index
2Journal of Medicinal Chemistry cover
Journal of Medicinal Chemistry
ISSN 0022-26231,691 articles in this topic
366h-index
3Bioorganic & Medicinal Chemistry Letters cover
Bioorganic & Medicinal Chemistry Letters
ISSN 0960-894X1,673 articles in this topic
179h-index
4Organic Letters cover
Organic Letters
ISSN 1523-70521,601 articles in this topic
267h-index
5Organic & Biomolecular Chemistry cover
Organic & Biomolecular Chemistry
ISSN 1477-05201,314 articles in this topic
188h-index
6European Journal of Medicinal Chemistry cover
European Journal of Medicinal Chemistry
ISSN 0223-52341,228 articles in this topic
233h-index
7
Molecules
ISSN 1420-30491,077 articles in this topic
330h-index
8European Journal of Organic Chemistry cover
European Journal of Organic Chemistry
ISSN 1099-06901,035 articles in this topic
184h-index
9Bioorganic & Medicinal Chemistry cover
Bioorganic & Medicinal Chemistry
ISSN 0968-08961,005 articles in this topic
199h-index
10Chemical Science cover
Chemical Science
ISSN 2041-6520542 articles in this topic
270h-index
11Chemical Society Reviews cover
Chemical Society Reviews
ISSN 0306-0012193 articles in this topic
745h-index
12Nature Chemistry cover
Nature Chemistry
ISSN 1755-4330165 articles in this topic
350h-index
13Nature Reviews Drug Discovery cover
Nature Reviews Drug Discovery
ISSN 1474-177695 articles in this topic
469h-index
14Journal of Research in Chemistry cover
Journal of Research in Chemistry
ISSN 2709-94153 articles in this topic
9h-index