Health Sciences → Medicine → Pharmacology
Inflammatory mediators and NSAID effects
This cluster of papers focuses on the use of cyclooxygenase-2 (COX-2) inhibitors, such as rofecoxib, celecoxib, and naproxen, in the context of inflammation and cancer. It explores the gastrointestinal and cardiovascular toxicity, chemopreventive effects, and potential risks associated with these drugs. The cluster also delves into the molecular biology of prostaglandins, particularly prostaglandin E2, and their role in modulating immune responses and promoting cancer growth.
96.6K works worldwide2.2M citations
Cyclooxygenase-2 InhibitorsInflammationCancerProstaglandinsNSAIDsCardiovascular RiskColorectal CancerChemopreventionProstaglandin E2COX-2
Journals publishing in this area
1
276h-index
3.61Impact
43.9KArticles
1.3MCitations
2
Journal of Pharmacology and Experimental Therapeutics
324h-index
0.94Impact
39.4KArticles
1.5MCitations
3
315h-index
3.77Impact
26.4KArticles
1.2MCitations
4
290h-index
3.81Impact
33.2KArticles
1.2MCitations
6
219h-index
1.81Impact
15.9KArticles
494.5KCitations
7
269h-index
2.99Impact
18.8KArticles
650.6KCitations
8
261h-index
2.18Impact
14.2KArticles
725KCitations
9
244h-index
3.19Impact
14.2KArticles
543.8KCitations
11
258h-index
2.19Impact
11.6KArticles
553.9KCitations
12
316h-index
8.15Impact
7.5KArticles
483.3KCitations
13
1h-index
0.03Impact
47Articles
2Citations