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Health Sciences → Medicine → Pharmacology

Inflammatory mediators and NSAID effects

This cluster of papers focuses on the use of cyclooxygenase-2 (COX-2) inhibitors, such as rofecoxib, celecoxib, and naproxen, in the context of inflammation and cancer. It explores the gastrointestinal and cardiovascular toxicity, chemopreventive effects, and potential risks associated with these drugs. The cluster also delves into the molecular biology of prostaglandins, particularly prostaglandin E2, and their role in modulating immune responses and promoting cancer growth.

96.6K works worldwide2.2M citations
Cyclooxygenase-2 InhibitorsInflammationCancerProstaglandinsNSAIDsCardiovascular RiskColorectal CancerChemopreventionProstaglandin E2COX-2

Journals publishing in this area

Articles on Scinovex in this research area

12 articles, most cited first

  1. Pyrrolidine-mediated prodrug strategy for ibuprofen: Synthesis, characterization and biological evaluation
    International Journal of Advanced Chemistry Research · 2026 · 0 citations · AI summary
  2. Peritoneal dialysis for management of meloxicam induced acute kidney injury in dog
    International Journal of Veterinary Sciences and Animal Husbandry · 2025 · 0 citations
  3. The effect of Tanacetum parthenium in orthopaedic mini-drill induced
    International Journal of Advanced Biochemistry Research · 2025 · 0 citations
  4. Effects of quercetin on meloxicam-induced haemato-biochemical alterations in male wistar rats
    International Journal of Advanced Biochemistry Research · 2025 · 0 citations
  5. Cyclooxygenase-mediated prostaglandin biosynthesis pathways: Implications for anti-inflammatory drug development and therapeutic targeting
    International Journal of Advanced Biochemistry Research · 2025 · 0 citations
  6. Eicosanoid biosynthesis including prostacyclin and thromboxane production in vascular endothelial cells: Regulation and pathophysiological significance
    International Journal of Advanced Biochemistry Research · 2025 · 0 citations
  7. Arachidonic acid release and eicosanoid cascade activation in platelet aggregation and thrombosis: Biochemical pathways and inhibitors
    International Journal of Advanced Biochemistry Research · 2025 · 0 citations
  8. Synthesis and structure-activity relationships of isoxazole-based anti-inflammatory agents
    International Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
  9. Synthesis and evaluation of curcumin analogues as dual COX-2/5-LOX inhibitors
    International Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
  10. Prodrug design of NSAIDs to minimize gastrointestinal side effects
    International Journal of Advanced Chemistry Research · 2025 · 0 citations · AI summary
  11. ALT Blood Test
    International Journal of Biology Sciences · 2019 · 0 citations · AI summary
  12. Topical NSAIDs in ocular surgery: A head-to-head trial of Nepafenac versus bromfenac after phacoemulsification
    International Journal of Advanced Biochemistry Research · 2017 · 0 citations