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Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids

European Journal of Medicinal Chemistry · 2014 · Vol. 77 · pp. 422–487
Kunal NepaliSahil SharmaManmohan SharmaPreet Mohinder Singh BediK.L. Dhar
Synthesis and Biological EvaluationSynthesis and biological activityCancer therapeutics and mechanismsPharmacophoreChemistryRational designComputational biologyHybridIsatinStructure–activity relationshipAnticancer drugTubulinDrug

MeSH terms

AnimalsAntineoplastic AgentsDrug Screening Assays, AntitumorHumansStructure-Activity RelationshipDrug DesignMolecular StructureCell Proliferation
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References
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HDAC family: What are the cancer relevant targets?
Cancer Letters · 2008 · 1,047 citations
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