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Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function
Molecular Cell · 2005 · Vol. 17(3) · pp. 393–403
Lin Chen✉(Walter and Eliza Hall Institute of Medical Research)Simon N. Willis(Walter and Eliza Hall Institute of Medical Research)Andrew H. Wei(Walter and Eliza Hall Institute of Medical Research)Brian J. Smith(Walter and Eliza Hall Institute of Medical Research)Jamie I. Fletcher(Walter and Eliza Hall Institute of Medical Research)Mark G. Hinds(Walter and Eliza Hall Institute of Medical Research)Peter M. Colman(Walter and Eliza Hall Institute of Medical Research)Catherine L. Day(University of Otago)Jerry M. Adams(Walter and Eliza Hall Institute of Medical Research)David C.S. Huang(Walter and Eliza Hall Institute of Medical Research)
Cell death mechanisms and regulationRNA Interference and Gene DeliveryComputational Drug Discovery MethodsPumaBiologyCell biologyApoptosisFunction (biology)Plasma protein bindingBcl-xLDNA-binding proteinProgrammed cell deathBiochemistry
MeSH terms
Bcl-2-Like Protein 11Amino Acid SequenceAnimalsBinding, CompetitiveCarrier ProteinsCell SurvivalGenetic Complementation TestHumansLigandsMembrane ProteinsModels, BiologicalModels, MolecularMolecular Sequence DataNeoplasm ProteinsPeptide Fragments
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BCL-2, BCL-XL Sequester BH3 Domain-Only Molecules Preventing BAX- and BAK-Mediated Mitochondrial Apoptosis
Molecular Cell · 2001 · 1,688 citations
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