article Open AccessTop 1% cited
BCL-2, BCL-XL Sequester BH3 Domain-Only Molecules Preventing BAX- and BAK-Mediated Mitochondrial Apoptosis
Molecular Cell · 2001 · Vol. 8(3) · pp. 705–711
Emily H. Cheng(Howard Hughes Medical Institute)Michael C. Wei(Howard Hughes Medical Institute)Solly Weiler(Howard Hughes Medical Institute)Richard A. Flavell(Howard Hughes Medical Institute)Tak W. Mak(Ontario Institute for Cancer Research)Tullia Lindsten(Cancer Research Institute)Stanley J. Korsmeyer✉(Howard Hughes Medical Institute)
Mitochondrial Function and PathologyCell death mechanisms and regulationATP Synthase and ATPases ResearchBiologyBcl-xLCell biologyApoptosisMitochondrionDomain (mathematical analysis)Bcl-2-associated X proteinProgrammed cell deathBiochemistryCaspase 3
MeSH terms
Bcl-2-Like Protein 11AnimalsCarrier ProteinsCell LineCytochrome c GroupEnzyme PrecursorsMembrane ProteinsMitochondriaProteinsProto-Oncogene ProteinsRecombinant ProteinsImmunoblottingApoptosisProtein Structure, TertiaryProto-Oncogene Proteins c-bcl-2
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Molecular and Cellular Biology · 2000 · 1,203 citations
Bim: a novel member of the Bcl-2 family that promotes apoptosis
The EMBO Journal · 1998 · 1,151 citations
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