review Open AccessTop 1% cited
The Bcl-2 apoptotic switch in cancer development and therapy
Oncogene · 2007 · Vol. 26(9) · pp. 1324–1337
Jerry M. Adams✉(Walter and Eliza Hall Institute of Medical Research)Suzanne Cory(Walter and Eliza Hall Institute of Medical Research)
Cell death mechanisms and regulationCancer-related Molecular PathwaysRNA Interference and Gene DeliveryPumaBiologyApoptosisCell biologyBcl-2 familyCancerCancer cellCarcinogenesisFunction (biology)Commit
MeSH terms
HumansNeoplasmsApoptosisMolecular MimicryProto-Oncogene Proteins c-bcl-2
Citations
2,149
FWCI
55.76
field-weighted impact
References
146
Percentile
100%
vs. same field & year
Citations per year
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References
Cell Death
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Cancer Cell · 2002 · 1,634 citations
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Cell Death and Differentiation · 2002 · 698 citations
Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
Current Biology · 2000 · 965 citations
The Combined Functions of Proapoptotic Bcl-2 Family Members Bak and Bax Are Essential for Normal Development of Multiple Tissues
Molecular Cell · 2000 · 1,468 citations
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
Cancer Cell · 2006 · 1,217 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
Live or let die: the cell's response to p53
Nature reviews. Cancer · 2002 · 3,179 citations
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