reviewTop 1% cited
Live or let die: the cell's response to p53
Nature reviews. Cancer · 2002 · Vol. 2(8) · pp. 594–604
Karen H. Vousden✉(National Cancer Institute)Xin Lü(Ludwig Cancer Research)
Cancer-related Molecular PathwaysCell death mechanisms and regulationUbiquitin and proteasome pathwaysProgrammed cell deathApoptosisCancer researchBiologyCellCell biologyMedicineGenetics
MeSH terms
AnimalsHumansNeoplasmsGene Expression Regulation, NeoplasticGenes, p53Apoptosis
Citations
3,179
FWCI
66.10
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References
148
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100%
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References
mdm2 expression is induced by wild type p53 activity.
The EMBO Journal · 1993 · 1,285 citations
PUMA, a Novel Proapoptotic Gene, Is Induced by p53
Molecular Cell · 2001 · 2,283 citations
WAF1, a potential mediator of p53 tumor suppression
Cell · 1993 · 8,369 citations
Mechanisms of p53-dependent apoptosis
Biochemical Society Transactions · 2001 · 533 citations
PUMA Induces the Rapid Apoptosis of Colorectal Cancer Cells
Molecular Cell · 2001 · 1,277 citations
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Genes & Development · 1996 · 2,349 citations
The p53-mdm-2 autoregulatory feedback loop.
Genes & Development · 1993 · 1,791 citations
NF-κB at the crossroads of life and death
Nature Immunology · 2002 · 2,690 citations
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