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Charles M. Perou

University of North Carolina at Chapel HillORCID https://orcid.org/0000-0001-9827-2247
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Top Publications

Molecular portraits of human breast tumours
Nature200016,173 citationsFirst authorCorresponding
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
Proceedings of the National Academy of Sciences200110,888 citations
Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
Cancer Cell20107,655 citations
The Immune Landscape of Cancer
Immunity20186,071 citations
Repeated observation of breast tumor subtypes in independent gene expression data sets
Proceedings of the National Academy of Sciences20035,398 citations
The Somatic Genomic Landscape of Glioblastoma
Cell20135,082 citations
The Somatic Genomic Landscape of Glioblastoma
Cell20135,082 citations
Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes
Journal of Clinical Oncology20094,815 citations
Race, Breast Cancer Subtypes, and Survival in the Carolina Breast Cancer Study
JAMA20063,808 citations
Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013
Annals of Oncology20133,672 citations
Immunohistochemical and Clinical Characterization of the Basal-Like Subtype of Invasive Breast Carcinoma
Clinical Cancer Research20042,652 citations
Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
Cancer Cell20102,346 citations
Ki67 Index, HER2 Status, and Prognosis of Patients With Luminal B Breast Cancer
JNCI Journal of the National Cancer Institute20092,199 citations
The Triple Negative Paradox: Primary Tumor Chemosensitivity of Breast Cancer Subtypes
Clinical Cancer Research20072,107 citations
Systematic variation in gene expression patterns in human cancer cell lines
Nature Genetics20002,090 citations
Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma
Cancer Cell20172,015 citations
Breast Cancer Molecular Subtypes Respond Differently to Preoperative Chemotherapy
Clinical Cancer Research20051,881 citations
Identification of Genes Periodically Expressed in the Human Cell Cycle and Their Expression in Tumors
Molecular Biology of the Cell20021,593 citations
The molecular portraits of breast tumors are conserved across microarray platforms
BMC Genomics20061,463 citations
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
Genome biology20071,260 citationsCorresponding
Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas
Cell Reports20181,209 citations
Basal-Like Breast Cancer Defined by Five Biomarkers Has Superior Prognostic Value than Triple-Negative Phenotype
Clinical Cancer Research20081,187 citations
Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images
Cell Reports20181,017 citations
Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival
Breast Cancer Research and Treatment2011905 citationsCorresponding
Epidemiology of basal-like breast cancer
Breast Cancer Research and Treatment2007892 citations
A Comparison of PAM50 Intrinsic Subtyping with Immunohistochemistry and Clinical Prognostic Factors in Tamoxifen-Treated Estrogen Receptor–Positive Breast Cancer
Clinical Cancer Research2010818 citations
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma
Cell Reports2018787 citations
Driver Fusions and Their Implications in the Development and Treatment of Human Cancers
Cell Reports2018640 citations
Endocrine-Therapy-Resistant ESR1 Variants Revealed by Genomic Characterization of Breast-Cancer-Derived Xenografts
Cell Reports2013618 citations
Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles
Cell Reports2017606 citations
Expression of Cytokeratins 17 and 5 Identifies a Group of Breast Carcinomas with Poor Clinical Outcome
American Journal Of Pathology2002563 citations
Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)
Breast Cancer Research and Treatment2011371 citations