article Open AccessTop 1% cited
The Somatic Genomic Landscape of Glioblastoma
Cell · 2013 · Vol. 155(2) · pp. 462–477
Cameron Brennan✉(Memorial Sloan Kettering Cancer Center)Roel G.W. Verhaak(The University of Texas MD Anderson Cancer Center)Aaron McKenna(Broad Institute)Benito Campos(Heidelberg University)Houtan Noushmehr(University of Southern California)Sofie R. Salama(University of California, Santa Cruz)Siyuan Zheng(The University of Texas MD Anderson Cancer Center)Debyani Chakravarty(Memorial Sloan Kettering Cancer Center)Zack Sanborn(University of California, Santa Cruz)Samuel Berman(Institute for Systems Biology)Rameen Beroukhim(The University of Texas MD Anderson Cancer Center)Brady Bernard(The University of Texas MD Anderson Cancer Center)Chang-Jiun Wu(Institute for Systems Biology)Giannicola Genovese(Case Western Reserve University)Ilya Shmulevich(Broad Institute)Jill S. Barnholtz‐Sloan(The University of Texas MD Anderson Cancer Center)Lihua Zou(Dana-Farber Cancer Institute)Rahulsimham Vegesna(Memorial Sloan Kettering Cancer Center)Sachet A. Shukla(The University of Texas MD Anderson Cancer Center)Giovanni Ciriello(The University of Texas MD Anderson Cancer Center)W. K. Alfred Yung(Broad Institute)Wei Zhang(Henry Ford Hospital)Carrie Sougnez(The University of Texas MD Anderson Cancer Center)Tom Mikkelsen(Duke Medical Center)Kenneth Aldape(Emory University)Darell D. Bigner(University of California, San Francisco)Erwin G. Van Meir(University Hospitals Cleveland Medical Center)Michael D. Prados(Cedars-Sinai Medical Center)Andrew E. Sloan(St. Joseph's Hospital and Medical Center)Keith L. Black(Fondazione IRCCS Istituto Neurologico Carlo Besta)Jennifer Eschbacher(University of Florida)Gaetano Finocchiaro(Thomas Jefferson University)William A. Friedman(Toronto Western Hospital)David W. Andrews(Christiana Care Health System)Abhijit Guha(Mayo Clinic in Arizona)Mary Iacocca(Swedish Medical Center)Brian Patrick O’Neill(Penrose-St. Francis Health Services)Greg Foltz(University of Southern California)Jerome MyersDaniel J. Weisenberger(Brigham and Women's Hospital)Robert Penny(University of North Carolina at Chapel Hill)Raju Kucherlapati(University of North Carolina at Chapel Hill)Charles M. Perou(Baylor College of Medicine)D. Neil Hayes(BC Cancer Agency)Richard A. Gibbs(The University of Texas MD Anderson Cancer Center)Marco A. Marra(Broad Institute)Gordon B. Mills(Oregon Health & Science University)Eric S. Lander(Washington University in St. Louis)Paul T. Spellman(Memorial Sloan Kettering Cancer Center)Richard K. Wilson(The University of Texas MD Anderson Cancer Center)Chris Sander(Broad Institute)John N. Weinstein(Broad Institute)Matthew Meyerson(University of Southern California)Stacey Gabriel(Howard Hughes Medical Institute)Peter W. Laird(Broad Institute)David Haussler(Broad Institute)Gad GetzLynda Chin(Case Western Reserve University)Christopher C. BenzJill S. Barnholtz‐SloanWendi BarrettQuinn T. Ostrom(Cedars-Sinai Medical Center)Yingli WolinskyKeith L. BlackBikash BosePaul T. Boulos(St. Joseph's Hospital and Medical Center)Madgy BoulosJenn Brown(Broad Institute)Christine Czerinski(Christiana Care Health System)Matthew EppleyMary IacoccaThelma KempistaTeresa KitkoYakov KoyfmanBrenda Rabeno(University of California, San Francisco)Pawan RastogiMichael C. SugarmanPatricia SwansonKennedy YalamanchiiIlana P. OteyYingchun Spring LiuYonghong XiaoJ. Todd AumanPeng‐Chieh ChenAngela HadjipanayisEunjung LeeSemin LeePeter J. ParkJonathan G. Seidman(Brigham and Women's Hospital)Lixing YangRaju Kucherlapati(Henry Ford Hospital)Steven N. KalkanisTom MikkelsenLaila PoissonAditya Raghunathan(Institute for Systems Biology)Lisa ScarpaceBrady BernardRyan BresslerAndrea EakinLisa IypeRichard KreisbergKalle LeinonenSheila M. ReynoldsHector Rovira(Institute for Systems Biology)Vésteinn ThórssonIlya ShmulevichMatti AnnalaRobert PennyJoseph PaulauskisErin Curley(Howard Hughes Medical Institute)Martha HatfieldDavid MalleryScott MorrisTroy SheltonCandace SheltonMark E. ShermanPeggy YenaLucia CuppiniFrancesco DiMeco(Fondazione IRCCS Istituto Neurologico Carlo Besta)Marica EoliGaetano FinocchiaroEmanuela Maderna(BC Cancer Agency)Bianca PolloMarco SainiSaianand Balu(University of Florida)Katherine A. HoadleyLing Li(Memorial Sloan Kettering Cancer Center)C. Ryan MillerYan Shi(The University of Texas MD Anderson Cancer Center)Michael D. TopalJunyuan WuGavin P. Dunn(Mayo Clinic in Arizona)Caterina GianniniBrian Patrick O’NeillBülent Arman AksoyYevgeniy Antipin(Memorial Sloan Kettering Cancer Center)Laetitia Borsu(Memorial Sloan Kettering Cancer Center)Samuel BermanCameron Brennan(Memorial Sloan Kettering Cancer Center)Ethan Cerami(Memorial Sloan Kettering Cancer Center)Debyani ChakravartyGiovanni CirielloJianjiong GaoBenjamin Groß(BC Cancer Agency)Anders J. SkanderupMarc LadanyiAlex LashYupu Liang(Memorial Sloan Kettering Cancer Center)Boris RevaChris SanderNikolaus SchultzRonglai ShenNicholas D. SocciAgnès VialeMartin L. Ferguson(The University of Texas MD Anderson Cancer Center)Qingrong ChenJohn A. DemchokLaura A. L. DillonKenna ShawMargi ShethRoy TarnuzzerLinghua WangLiming YangTanja M. DavidsenMark S. GuyerBradley A. OzenbergerHeidi J. Sofia(The University of Texas MD Anderson Cancer Center)Julie BergstenJohn Eckman(Penrose-St. Francis Health Services)Jodi HarrJerome MyersChristine SmithKelly J. Tucker(University of California, Santa Cruz)Cindy WinemillerLeigh Anne Zach(Swedish Medical Center)Julia Y. LjubimovaGreg EleyBrenda AyalaMark A. JensenA Kahn(Howard Hughes Medical Institute)Todd Pihl(Thomas Jefferson University)David Pot(St. Joseph's Hospital and Medical Center)Yunhu Wan(Swedish Medical Center)Jennifer EschbacherGreg FoltzNathan HansenParvi HothiBiaoyang LinNameeta ShahJae‐Geun Yoon(University of California, San Francisco)Ching C. LauMichael E. Berens(Broad Institute)Kristin ArdlieRameen BeroukhimScott L. CarterAndrew D. CherniackMike NobleJuok Cho(University of Southern California)Kristian CibulskisDaniel DiCara(Broad Institute)Scott FrazerStacey GabrielNils Gehlenborg(Howard Hughes Medical Institute)Jeff GentryDavid I. HeimanJaegil Kim(Broad Institute)Rui Jing(University of California, San Francisco)Eric S. LanderMichael S. Lawrence(University of Florida)Pei Lin(Broad Institute)Will MallardMatthew Meyerson(The University of Texas MD Anderson Cancer Center)Robert C. OnofrioGordon Saksena(Broad Institute)Steve SchumacherCarrie SougnezPetar StojanovBarbara Tabak(The University of Texas MD Anderson Cancer Center)Doug Voet(Broad Institute)Hailei Zhang(Broad Institute)Lihua ZouGad Getz(University of Florida)Nathan N. DeesJun LiLucinda FultonRobert S. FultonKrishna-Latha Kanchi(Washington University in St. Louis)Elaine R. MardisRichard K. Wilson(Thomas Jefferson University)Stephen B. BaylinDavid W. AndrewsLarry A. HarshyneMark L. Cohen(University Hospitals Cleveland Medical Center)Karen DevineAndrew E. Sloan(University of Southern California)Scott R. VandenBerg(University of California, San Francisco)Mitchel S. Berger(University of Southern California)Michael D. Prados(Mayo Clinic in Arizona)Daniel CarlinBrian Craft(Christiana Care Health System)Kyle EllrottMary J. GoldmanTheodore C. Goldstein(Howard Hughes Medical Institute)Mia Grifford(Broad Institute)David Haussler(Emory University)Singer Ma(University of California, Santa Cruz)Sam Ng(University of California, Santa Cruz)Sofie R. SalamaZack SanbornJoshua M. Stuart(University of Southern California)Teresa SwatloskiPeter WaltmanJing ZhuRobin M. Foss(University of Florida)Barbara FrentzenWilliam A. FriedmanRaquel G. McTiernan(University of North Carolina at Chapel Hill)Anthony T. Yachnis(University of North Carolina at Chapel Hill)D. Neil Hayes(The University of Texas MD Anderson Cancer Center)Charles M. Perou(The University of Texas MD Anderson Cancer Center)Siyuan ZhengRahulsimham VegesnaYong Mao(The University of Texas MD Anderson Cancer Center)Rehan AkbaniKenneth AldapeOliver BöglerGregory N. FullerWenbin LiuYuexin Liu(The University of Texas MD Anderson Cancer Center)Yiling LuGordon B. Mills(Memorial Sloan Kettering Cancer Center)Alexei ProtopopovXiaojia Ren(The University of Texas MD Anderson Cancer Center)Youting Sun(The University of Texas MD Anderson Cancer Center)Chang-Jiun Wu(The University of Texas MD Anderson Cancer Center)W. K. Alfred Yung(The University of Texas MD Anderson Cancer Center)Wei Zhang(The University of Texas MD Anderson Cancer Center)Jianhua Zhang(The University of Texas MD Anderson Cancer Center)Ken Chen(Broad Institute)John N. Weinstein(The University of Texas MD Anderson Cancer Center)Lynda Chin(University of Southern California)Roel G.W. Verhaak(University of Southern California)Houtan NoushmehrDaniel J. Weisenberger(University of Southern California)Moiz S. BootwallaPhillip H. LaiTimothy J. Triche(University of Southern California)David Van Den Berg(Howard Hughes Medical Institute)Peter W. LairdDavid H. Gutmann(Emory University)Norman L. Lehman(University of Southern California)Erwin G. Van MeirDaniel J. BratJeffrey J. OlsonGena M. Mastrogianakis(The University of Texas MD Anderson Cancer Center)Narra S. Devi(Duke Medical Center)Zhaobin Zhang(Broad Institute)Darell D. BignerEric LippRoger E. McLendon
Glioma Diagnosis and TreatmentCancer Genomics and DiagnosticsMicroRNA in disease regulationBiologySomatic cellGlioblastomaGeneticsComputational biologyEvolutionary biologyCancer researchGene
MeSH terms
Brain NeoplasmsFemaleGlioblastomaHumansMaleMutationSignal TransductionProteomeGene Expression ProfilingGene Regulatory Networks
Citations
5,082
FWCI
137.81
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References
81
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100%
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miR-29 miRNAs activate p53 by targeting p85α and CDC42
Nature Structural & Molecular Biology · 2008 · 604 citations
Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway
PLoS Genetics · 2012 · 630 citations
Most mammalian mRNAs are conserved targets of microRNAs
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Molecular Cell · 2007 · 3,788 citations
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Nature Reviews Genetics · 2010 · 4,666 citations
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