article Open AccessTop 1% cited
MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing
Molecular Cell · 2007 · Vol. 27(1) · pp. 91–105
Andrew Grimson(Whitehead Institute for Biomedical Research)Kyle Kai‐How Farh(Howard Hughes Medical Institute)Wendy K. Johnston(Massachusetts Institute of Technology)Philip W. Garrett-Engele(Rosetta Stone (United States))Lee P. Lim✉(Rosetta Stone (United States))David P. Bartel✉(Massachusetts Institute of Technology)
MicroRNA in disease regulationRNA Research and SplicingRNA Interference and Gene DeliveryBiologymicroRNAContext (archaeology)Psychological repressionUntranslated regionComputational biologyThree prime untranslated regionGeneticsSite of actionNucleotide
MeSH terms
AnimalsBase SequenceBinding SitesHeLa CellsHumansMammalsModels, GeneticMolecular Sequence DataNucleotidesRNA, MessengerSubstrate SpecificityDown-RegulationConserved SequenceCodon, TerminatorBase Pairing
Funding
- Howard Hughes Medical Institute
- Merck
- National Institutes of Health
Citations
3,788
FWCI
91.41
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References
36
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100%
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Nature Biotechnology · 2003 · 2,360 citations
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PLoS Biology · 2004 · 3,885 citations
Combinatorial microRNA target predictions
Nature Genetics · 2005 · 4,610 citations
Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets
Cell · 2005 · 11,901 citations
Specificity of microRNA target selection in translational repression
Genes & Development · 2004 · 1,627 citations
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