review Open AccessTop 1% cited

The PI3K–AKT network at the interface of oncogenic signalling and cancer metabolism

Nature reviews. Cancer · 2019 · Vol. 20(2) · pp. 74–88

Gerta Hoxhaj✉(Harvard University)Brendan D. Manning(Harvard University)

Cancer, Hypoxia, and Metabolism Metabolism, Diabetes, and Cancer PI3K/AKT/mTOR signaling in cancerPI3K/AKT/mTOR pathwayBiologyCell biologyProtein kinase BCancer cellSignal transductionCell growthCancerBiochemistryGenetics

MeSH terms

AnimalsDisease SusceptibilityEnergy MetabolismGlucoseHumansNeoplasmsOxidation-ReductionSignal TransductionOncogene ProteinsGene Expression Regulation, NeoplasticPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-akt

Citations

2,067

FWCI

62.72

field-weighted impact

References

203

Percentile

100%

vs. same field & year

Citations per year

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