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Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma

Journal of Clinical Oncology · 2009 · Vol. 27(28) · pp. 4733–4740
Henry S. FriedmanMichael D. PradosPatrick Y. WenTom MikkelsenDavid SchiffLauren E. AbreyW.K. Alfred YungNina A. PaleologosM. Kelly NicholasRandy L. JensenJames J. VredenburghJane HuangMaoxia ZhengTimothy F. Cloughesy

Abstract

Bevacizumab, alone or in combination with irinotecan, was well tolerated and active in recurrent glioblastoma.

Glioma Diagnosis and TreatmentCancer Treatment and PharmacologyCancer, Hypoxia, and MetabolismMedicineBevacizumabIrinotecanGlioblastomaOncologyInternal medicineSurgeryChemotherapyCancerColorectal cancer

MeSH terms

BevacizumabIrinotecanAdultAgedAntibodies, MonoclonalAntineoplastic Combined Chemotherapy ProtocolsBrain NeoplasmsCamptothecinDrug Administration ScheduleFemaleGlioblastomaHumansMaleMiddle AgedNeoplasm Recurrence, Local
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