article Open AccessTop 1% cited
Factors Influencing the Composition of the Intestinal Microbiota in Early Infancy
PEDIATRICS · 2006 · Vol. 118(2) · pp. 511–521
John Penders✉(Maastricht University)Carel Thijs(Maastricht University)Cornelis Vink(Maastricht University Medical Centre)Foekje F. Stelma(Maastricht University Medical Centre)Bianca E.P. Snijders(Maastricht University)Ischa Kummeling(Maastricht University)Piet A. van den Brandt(Maastricht University)Ellen E. Stobberingh(Maastricht University Medical Centre)
Abstract
The most important determinants of the gut microbiotic composition in infants were the mode of delivery, type of infant feeding, gestational age, infant hospitalization, and antibiotic use by the infant. Term infants who were born vaginally at home and were breastfed exclusively seemed to have the most "beneficial" gut microbiota (highest numbers of bifidobacteria and lowest numbers of C difficile and E coli).
Gut microbiota and healthPediatric health and respiratory diseasesProbiotics and Fermented FoodsMedicineBacteroidesGut floraFecesBifidobacteriumClostridium difficileBacteroides fragilisGestational ageAntibioticsPhysiology
MeSH terms
AdultAnti-Bacterial AgentsAntifungal AgentsBacteriaBacteroides fragilisBifidobacteriumBreast FeedingCesarean SectionEscherichia coliFecesFemaleFeverGestational AgeHome ChildbirthHospitalization
Citations
2,202
FWCI
17.10
field-weighted impact
References
46
Percentile
100%
vs. same field & year
Citations per year
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References
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FEMS Microbiology Letters · 2004 · 379 citations
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Thorax · 2000 · 1,179 citations
Determination of bacterial load by real-time PCR using a broad-range (universal) probe and primers set
Microbiology · 2002 · 1,966 citations
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