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Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study

BJOG An International Journal of Obstetrics & Gynaecology · 2015 · Vol. 123(6) · pp. 983–993

Meghan B. Azad(University of Manitoba)Theodore Konya(University of Toronto)RR Persaud(University of Manitoba)DS Guttman(University of Toronto)RS Chari(University of Alberta)Catherine J. Field(University of Alberta)MR Sears(McMaster University)PJ Mandhane(University of Alberta)SE Turvey(BC Children's Hospital)Padmaja Subbarao(Hospital for Sick Children)A.B. Becker(Children's Hospital Research Institute of Manitoba)James A. Scott(Public Health Ontario)Anita L. Kozyrskyj✉(University of Alberta)the CHILD Study Investigators

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Abstract

Maternal #antibiotics during childbirth alter the infant gut #microbiome.

Gut microbiota and health Urinary Tract Infections Management Clostridium difficile and Clostridium perfringens researchBreastfeedingMedicineGut floraDysbiosisProspective cohort studyPregnancyCohort studyCaesarean sectionCohortBreast feeding

MeSH terms

Gastrointestinal MicrobiomeAnti-Bacterial AgentsBacteroidesBreast FeedingCesarean SectionClostridiumFecesFemalePremature Rupture of Fetal MembranesFetal Membranes, Premature RuptureHumansInfantPregnancyProspective StudiesStreptococcal Infections