reviewTop 1% cited

The influence of drug-like concepts on decision-making in medicinal chemistry

Nature Reviews Drug Discovery · 2007 · Vol. 6(11) · pp. 881–890

Paul D. Leeson✉(AstraZeneca (Singapore))Brian Springthorpe(Loughborough University)

Computational Drug Discovery Methods Pharmacogenetics and Drug Metabolism Pharmaceutical Economics and PolicyDrug discoveryAttritionDrugDrug developmentMainstreamPharmacologyChemistryMedicinePolitical scienceBiochemistry

MeSH terms

Chemistry, PharmaceuticalDecision MakingPharmaceutical PreparationsHumansWater1-Octanol

Funding

AstraZeneca
Merck

Citations

2,269

FWCI

89.65

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

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References

Can the pharmaceutical industry reduce attrition rates?

Nature Reviews Drug Discovery · 2004 · 4,081 citations

A Bioavailability Score

Journal of Medicinal Chemistry · 2005 · 963 citations

Hydrogen Bonding. 32. An Analysis of Water-Octanol and Water-Alkane Partitioning and the Δlog P Parameter of Seiler

Journal of Pharmaceutical Sciences · 1994 · 759 citations

Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Journal of Medicinal Chemistry · 2002 · 7,875 citations

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1

Advanced Drug Delivery Reviews · 2001 · 17,620 citations

ADMET in silico modelling: towards prediction paradise?

Nature Reviews Drug Discovery · 2003 · 1,819 citations

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Advanced Drug Delivery Reviews · 1997 · 11,043 citations

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