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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
Advanced Drug Delivery Reviews · 2001 · Vol. 46(1-3) · pp. 3–26
Christopher A. Lipinski✉(Pfizer (United States))Franco Lombardo(Pfizer (United States))Beryl W. Dominy(Pfizer (United States))Paul J. Feeney(Pfizer (United States))
Crystallization and Solubility StudiesAnalytical Chemistry and ChromatographyDrug Solubulity and Delivery SystemsSolubilityDrug discoveryThermodynamicsChemistryPermeability (electromagnetism)Computational chemistryPhysicsOrganic chemistry
MeSH terms
AdsorptionChemistry, PhysicalComputersPharmaceutical PreparationsPermeabilityPharmacologySolubilityThermodynamicsChemical Phenomena
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References
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Journal of Pharmaceutical Sciences · 1994 · 759 citations
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Chemical Society Reviews · 1993 · 2,105 citations
Simple Method of Calculating Octanol/Water Partition Coefficient.
Chemical and Pharmaceutical Bulletin · 1992 · 523 citations
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