reviewTop 1% cited
Targeting multidrug resistance in cancer
Nature Reviews Drug Discovery · 2006 · Vol. 5(3) · pp. 219–234
Gergely Szakács✉(Hungarian Academy of Sciences)Jill K. Paterson(National Institutes of Health)Joseph A. Ludwig(National Cancer Institute)Catherine Booth-Genthe(National Institutes of Health)Michael M. Gottesman(National Institutes of Health)
Drug Transport and Resistance MechanismsHIV/AIDS drug development and treatmentCancer therapeutics and mechanismsEffluxATP-binding cassette transporterMultiple drug resistanceDrug resistanceCancerPharmacologyDrug discoveryDrugCancer cellTransporter
MeSH terms
AnimalsAntineoplastic AgentsHumansNeoplasmsDrug Resistance, MultipleATP-Binding Cassette TransportersDrug Resistance, Neoplasm
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References
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Molecular Pharmacology · 1999 · 680 citations
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Active outward transport of daunomycin in resistant ehrlich ascites tumor cells
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Localisation of breast cancer resistance protein in microvessel endothelium of human brain
Neuroreport · 2002 · 407 citations
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1976 · 3,268 citations
Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.
Journal of Histochemistry & Cytochemistry · 1990 · 1,070 citations
The Human ATP-Binding Cassette (ABC) Transporter Superfamily
Genome Research · 2001 · 1,739 citations
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