article Open AccessTop 1% cited
PTEN/PI3K/Akt Pathway Regulates the Side Population Phenotype and ABCG2 Activity in Glioma Tumor Stem-like Cells
Cell stem cell · 2009 · Vol. 4(3) · pp. 226–235
Anne-Marie Bleau(Memorial Sloan Kettering Cancer Center)Dolores Hambardzumyan(Memorial Sloan Kettering Cancer Center)Tatsuya Ozawa(Memorial Sloan Kettering Cancer Center)Elena I. Fomchenko(Memorial Sloan Kettering Cancer Center)Jason T. Huse(Memorial Sloan Kettering Cancer Center)Cameron Brennan(Memorial Sloan Kettering Cancer Center)Eric C. Holland✉(Memorial Sloan Kettering Cancer Center)
Drug Transport and Resistance MechanismsMicroRNA in disease regulationHedgehog Signaling Pathway StudiesSide populationPTENAbcg2BiologyPI3K/AKT/mTOR pathwayCancer researchGliomaProtein kinase BStem cellPopulation
MeSH terms
ATP Binding Cassette Transporter, Subfamily G, Member 2TemozolomidePhosphoinositide-3 Kinase InhibitorsAnimalsAntineoplastic AgentsBlood-Brain BarrierBrainCells, CulturedChromonesDacarbazineEnzyme InhibitorsGliomaHumansMice, NudeMitoxantrone
Funding
- National Institutes of Health
Citations
796
FWCI
38.54
field-weighted impact
References
32
Percentile
100%
vs. same field & year
Citations per year
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References
Side Population in Human Lung Cancer Cell Lines and Tumors Is Enriched with Stem-like Cancer Cells
Cancer Research · 2007 · 945 citations
Targeting multidrug resistance in cancer
Nature Reviews Drug Discovery · 2006 · 3,630 citations
Tumour stem cells and drug resistance
Nature reviews. Cancer · 2005 · 3,647 citations
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.
The Journal of Experimental Medicine · 1996 · 2,896 citations
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