review Open AccessTop 1% cited
Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia
Cancer Cell · 2014 · Vol. 26(5) · pp. 605–622
Rakesh K. Jain✉(Harvard University)
Angiogenesis and VEGF in CancerCancer, Hypoxia, and MetabolismCancer Genomics and DiagnosticsHypoxia (environmental)Cancer researchMedicineInternal medicineBiologyPharmacologyChemistryOxygen
MeSH terms
AnimalsDrug SynergismHumansImmunotherapyNeoplasmsNeovascularization, PathologicCell HypoxiaDrug Resistance, NeoplasmAngiogenesis Inhibitors
Citations
1,503
FWCI
42.71
field-weighted impact
References
198
Percentile
100%
vs. same field & year
Citations per year
Cited by
Cell Adhesion and Matrix Stiffness: Coordinating Cancer Cell Invasion and Metastasis
Frontiers in Oncology · 2018 · 387 citations
Contribution of Angiogenesis to Inflammation and Cancer
Frontiers in Oncology · 2019 · 307 citations
Resistance Mechanisms to Anti-angiogenic Therapies in Cancer
Frontiers in Oncology · 2020 · 375 citations
Targeting VEGF/VEGFR to Modulate Antitumor Immunity
Frontiers in Immunology · 2018 · 613 citations
Combined antiangiogenic and anti–PD-L1 therapy stimulates tumor immunity through HEV formation
Science Translational Medicine · 2017 · 771 citations
The clinical role of the TME in solid cancer
British Journal of Cancer · 2018 · 736 citations
References
Angiogenesis in cancer and other diseases
Nature · 2000 · 8,970 citations
Tumor-Associated Macrophages: From Mechanisms to Therapy
Immunity · 2014 · 3,967 citations
Sorafenib in Advanced Hepatocellular Carcinoma
New England Journal of Medicine · 2008 · 12,835 citations
Vascular Normalization by Vascular Endothelial Growth Factor Receptor 2 Blockade Induces a Pressure Gradient Across the Vasculature and Improves Drug Penetration in Tumors
Cancer Research · 2004 · 1,179 citations
Tumor Angiogenesis: Therapeutic Implications
New England Journal of Medicine · 1971 · 10,087 citations
Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients
Clinical Cancer Research · 2009 · 852 citations
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial
The Lancet Oncology · 2008 · 5,801 citations
Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
Cancer Cell · 2014 · 1,973 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.