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Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial

The Lancet Oncology · 2008 · Vol. 10(1) · pp. 25–34
Ann‐Lii ChengYoon‐Koo KangZhendong ChenChao-Jung TsaoShukui QinJun Suk KimRongcheng LuoJifeng FengSheng‐Long YeTsai‐Sheng YangJianming XuYan SunHoujie LiangJiwei LiuJiejun WangWon Young TakHongming PanK. BurockJ. ZouD. VoliotisZhongzhen Guan
Hepatocellular Carcinoma Treatment and PrognosisCancer Mechanisms and TherapyLiver physiology and pathologySorafenibHepatocellular carcinomaPlaceboMedicineDouble blindInternal medicinePhase (matter)OncologyAlternative medicinePathology

MeSH terms

SorafenibAdultAgedAged, 80 and overAntineoplastic AgentsBenzenesulfonatesCost-Benefit AnalysisDouble-Blind MethodFemaleCarcinoma, HepatocellularHumansLiver NeoplasmsMaleMiddle AgedNiacinamide

Funding

  • Bayer HealthCare
Citations
5,801
FWCI
85.25
field-weighted impact
References
42
Percentile
100%
vs. same field & year
Citations per year
References
Sorafenib in Advanced Hepatocellular Carcinoma
New England Journal of Medicine · 2008 · 12,835 citations
Transection of the oesophagus for bleeding oesophageal varices
British journal of surgery · 1973 · 7,910 citations
Discovery and development of sorafenib: a multikinase inhibitor for treating cancer
Nature Reviews Drug Discovery · 2006 · 1,812 citations
Global cancer statistics in the year 2000
The Lancet Oncology · 2001 · 2,455 citations
New Guidelines to Evaluate the Response to Treatment in Solid Tumors
JNCI Journal of the National Cancer Institute · 2000 · 15,689 citations
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