article Open AccessTop 1% cited
Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance
Cell Metabolism · 2008 · Vol. 7(1) · pp. 45–56
Timothy R. Koves✉(Duke University)John R. Ussher(University of Alberta)Robert C. Noland(Duke University)Dorothy H. Slentz(Duke University)Merrie Mosedale(Duke University)Olga Ilkayeva(Duke University)James R. Bain(Duke University)Robert D. Stevens(Duke University)Jason R.B. Dyck(University of Alberta)Christopher B. Newgard(Duke University)Gary D. Lopaschuk(University of Alberta)Deborah M. Muoio(Duke University)
Adipose Tissue and MetabolismMuscle metabolism and nutritionMitochondrial Function and PathologyInsulin resistanceSkeletal muscleBeta oxidationMitochondrionInternal medicineEndocrinologyFatty acidBiochemistryChemistryBiology
MeSH terms
AnimalsBlood GlucoseCarboxy-LyasesCell LineDietary FatsFatty AcidsGlucose Tolerance TestInsulin ResistanceMitochondriaObesityOxidation-ReductionMice, KnockoutMuscle, SkeletalMuscle Fibers, SkeletalLipid Metabolism
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Inhibition of Ceramide Synthesis Ameliorates Glucocorticoid-, Saturated-Fat-, and Obesity-Induced Insulin Resistance
Cell Metabolism · 2007 · 1,201 citations
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Nature Genetics · 2003 · 10,482 citations
Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss
American Journal of Physiology-Endocrinology and Metabolism · 1999 · 1,087 citations
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