articleTop 1% cited

PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

Nature Genetics · 2003 · Vol. 34(3) · pp. 267–273

Vamsi K. Mootha✉(Whitehead Institute for Biomedical Research)Cecilia M. Lindgren(Whitehead Institute for Biomedical Research)Karl‐Fredrik Eriksson(Lund University)Aravind Subramanian(Whitehead Institute for Biomedical Research)Smita Sihag(Whitehead Institute for Biomedical Research)Joseph Lehár(Whitehead Institute for Biomedical Research)Pere Puigserver(Harvard University)Emma Carlsson(Lund University)Martin Ridderstråle(Lund University)Esa Laurila(Lund University)Nicholas Houstis(Whitehead Institute for Biomedical Research)Mark J. Daly(Whitehead Institute for Biomedical Research)Nick Patterson(Whitehead Institute for Biomedical Research)Jill P. Mesirov(Whitehead Institute for Biomedical Research)Todd R. Golub(Dana-Farber Cancer Institute)Pablo Tamayo(Whitehead Institute for Biomedical Research)Bruce M. Spiegelman(Harvard University)Eric S. Lander(Massachusetts Institute of Technology)Joel N. Hirschhorn(Harvard University)David Altshuler(Harvard University)Leif Groop(Lund University)

View via DOI Publisher page

Metabolism, Diabetes, and Cancer Gene expression and cancer classification Bioinformatics and Genomic NetworksBiologyGeneDNA microarrayGene expression profilingGene expressionOxidative phosphorylationGeneticsRegulation of gene expressionComputational biologyBiochemistry

MeSH terms

AnimalsCells, CulturedDiabetes Mellitus, Type 2GlucoseGlucose Tolerance TestHumansInsulinMaleOxidative PhosphorylationRNA, MessengerTranscription FactorsDown-RegulationMuscle, SkeletalOligonucleotide Array Sequence AnalysisGene Expression Profiling

Citations

10,482

FWCI

56.27

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

Cited by

Role of Mitochondrial Dysfunction in Insulin Resistance