review Open AccessTop 1% cited

Role of BNIP3 and NIX in cell death, autophagy, and mitophagy

Cell Death and Differentiation · 2009 · Vol. 16(7) · pp. 939–946

Mingjie Zhang✉(St. Jude Children's Research Hospital)Paul A. Ney(St. Jude Children's Research Hospital)

Autophagy in Disease and Therapy Toxoplasma gondii Research Studies Mitochondrial Function and PathologyMitophagyAutophagyCell biologyProgrammed cell deathMitochondrionBiologyHypoxia (environmental)CellApoptosisChemistry

MeSH terms

AnimalsAutophagyHeart DiseasesHumansMembrane ProteinsMitochondriaNeoplasmsProto-Oncogene ProteinsCell HypoxiaCell DeathProtein Structure, TertiaryMitochondrial ProteinsTumor Suppressor ProteinsMiceRats

Funding

National Institutes of Health

Citations

999

FWCI

18.35

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

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References

Protection against Fatal Sindbis Virus Encephalitis by Beclin, a Novel Bcl-2-Interacting Protein

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FoxO3 Controls Autophagy in Skeletal Muscle In Vivo

Cell Metabolism · 2007 · 1,898 citations

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized

Cancer Cell · 2006 · 1,217 citations

Autophagy: molecular machinery for self-eating

Cell Death and Differentiation · 2005 · 1,525 citations

Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy

Cell Death and Differentiation · 2006 · 603 citations

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

Journal of Clinical Investigation · 2003 · 2,194 citations

Selective degradation of mitochondria by mitophagy

Archives of Biochemistry and Biophysics · 2007 · 1,506 citations

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

The EMBO Journal · 2008 · 3,057 citations

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