reviewTop 1% cited
Exploiting tumour hypoxia in cancer treatment
Nature reviews. Cancer · 2004 · Vol. 4(6) · pp. 437–447
J. Martin Brown✉(Stanford University)William R. Wilson(Cancer Society of New Zealand)
Cancer, Hypoxia, and MetabolismCancer Research and TreatmentsVirus-based gene therapy researchHypoxia (environmental)ProdrugRadiation therapyCancer researchNecrosisGenetic enhancementChemotherapyTranscription factorTumor hypoxiaCancer therapy
MeSH terms
Bacteria, AnaerobicDNA-Binding ProteinsHumansNecrosisNeoplasmsNuclear ProteinsProdrugsTranscription FactorsGenetic TherapyCell HypoxiaHelix-Loop-Helix MotifsDrug Resistance, NeoplasmHypoxia-Inducible Factor 1Hypoxia-Inducible Factor 1, alpha Subunit
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References
Hypoxia — a key regulatory factor in tumour growth
Nature reviews. Cancer · 2002 · 5,147 citations
Oxygenation predicts radiation response and survival in patients with cervix cancer
Radiotherapy and Oncology · 1998 · 601 citations
Targeting HIF-1 for cancer therapy
Nature reviews. Cancer · 2003 · 6,642 citations
The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour
British Journal of Cancer · 1968 · 768 citations
The Histological Structure of Some Human Lung Cancers and the Possible Implications for Radiotherapy
British Journal of Cancer · 1955 · 2,210 citations
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
Cancer Cell · 2003 · 1,293 citations
Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome
Radiotherapy and Oncology · 1999 · 545 citations
The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages
American Journal Of Pathology · 2000 · 1,298 citations
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