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Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

Cancer Cell · 2003 · Vol. 3(4) · pp. 347–361
Selma PennacchiettiPaolo MichieliLaura GalluzzoMassimiliano MazzoneSilvia GiordanoPaolo M. Comoglio
Cancer, Hypoxia, and MetabolismLipid metabolism and biosynthesisPancreatic function and diabetesHypoxia (environmental)Cell biologyBiologyCancer researchChemistryOxygen

MeSH terms

HypoxiaBase SequenceCell MovementCells, CulturedFluorescent Antibody TechniqueHumansMolecular Sequence DataNeoplasm InvasivenessPromoter Regions, GeneticRNA, MessengerTranscription, GeneticTumor Cells, CulturedBlotting, NorthernBlotting, WesternHepatocyte Growth Factor

Funding

  • Ministerio de Economía y Competitividad
  • Australasian Society for Human Biology
Citations
1,293
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112
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100%
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Citations per year
References
Hypoxia — a key regulatory factor in tumour growth
Nature reviews. Cancer · 2002 · 5,147 citations
Dissemination and growth of cancer cells in metastatic sites
Nature reviews. Cancer · 2002 · 3,915 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck
International Journal of Radiation Oncology*Biology*Physics · 1997 · 1,066 citations
Tumor Hypoxia: Definitions and Current Clinical, Biologic, and Molecular Aspects
JNCI Journal of the National Cancer Institute · 2001 · 2,637 citations
Disruption of epithelial cell-matrix interactions induces apoptosis
The Journal of Cell Biology · 1994 · 3,247 citations
Anoikis mechanisms
Current Opinion in Cell Biology · 2001 · 1,201 citations
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