reviewTop 1% cited
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
Oncogene · 2004 · Vol. 23(18) · pp. 3151–3171
Diane C. Fingar✉(Harvard University)John Blenis(Harvard University)
PI3K/AKT/mTOR signaling in cancerPolyamine Metabolism and ApplicationsTuberous Sclerosis Complex ResearchBiologyRHEBTOR signalingPI3K/AKT/mTOR pathwayCell cycleCell biologyMechanistic target of rapamycinRibosomal protein s6Cell growthKinase
MeSH terms
Ras Homolog Enriched in Brain ProteinTuberous Sclerosis Complex 1 ProteinTuberous Sclerosis Complex 2 ProteinAnimalsCarrier ProteinsCell CycleCell DivisionHumansNeoplasmsNeuropeptidesPhosphoproteinsProtein KinasesProteinsRepressor ProteinsRibosomes
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References
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Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
Genes & Development · 2003 · 1,900 citations
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