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ERBB receptors and cancer: the complexity of targeted inhibitors

Nature reviews. Cancer · 2005 · Vol. 5(5) · pp. 341–354
Nancy E. HynesHeidi A. Lane
HER2/EGFR in Cancer ResearchMonoclonal and Polyclonal Antibodies ResearchPI3K/AKT/mTOR signaling in cancerErbBReceptorReceptor tyrosine kinaseEpidermal growth factor receptorCancer researchTyrosine kinaseCancerBiologyGrowth factor receptor inhibitorGrowth factor receptor

MeSH terms

AnimalsAntibodies, MonoclonalAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsHumansNeoplasmsSignal TransductionDrug Delivery SystemsReceptor, ErbB-2Erb-b2 Receptor Tyrosine KinasesDrug Resistance, NeoplasmReceptor Protein-Tyrosine Kinases
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