reviewTop 1% cited
P-glycoprotein: from genomics to mechanism
Oncogene · 2003 · Vol. 22(47) · pp. 7468–7485
Suresh V. Ambudkar✉(Center for Cancer Research)Chava Kimchi‐Sarfaty(Center for Cancer Research)Zuben E. Sauna(National Cancer Institute)Michael M. Gottesman(Center for Cancer Research)
Drug Transport and Resistance MechanismsHIV/AIDS drug development and treatmentTrace Elements in HealthBiologyATP-binding cassette transporterP-glycoproteinEffluxGeneDrugDrug metabolismBiochemistryXenobioticMultidrug resistance-associated protein 2
MeSH terms
Binding SitesHumansGene Expression Regulation, NeoplasticProtein Structure, TertiaryDrug Resistance, MultipleATP Binding Cassette Transporter, Subfamily B, Member 1
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References
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Nature reviews. Cancer · 2002 · 5,468 citations
Expression of Multidrug Resistance Gene in Human Cancers
JNCI Journal of the National Cancer Institute · 1989 · 1,297 citations
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects
Clinical Pharmacology & Therapeutics · 2001 · 749 citations
From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance
Cellular and Molecular Life Sciences · 2001 · 685 citations
A Family of Drug Transporters: the Multidrug Resistance-Associated Proteins
JNCI Journal of the National Cancer Institute · 2000 · 1,754 citations
BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER
Annual Review of Biochemistry · 1993 · 3,504 citations
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