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Reactive oxygen species and cancer paradox: To promote or to suppress?

Free Radical Biology and Medicine · 2017 · Vol. 104 · pp. 144–164
Sehamuddin GaladariAnees RahmanSiraj PallichankandyFaisal Thayyullathil
Ferroptosis and cancer prognosisGenomics, phytochemicals, and oxidative stressCancer, Lipids, and MetabolismReactive oxygen speciesNecroptosisCancer cellCancerMitochondrial ROSCarcinogenesisProgrammed cell deathCancer researchCell biologyBiology

MeSH terms

Antineoplastic AgentsAntioxidantsAutophagyHumansNeoplasmsApoptosisReactive Oxygen SpeciesDrug Resistance, Neoplasm

Funding

  • Al Jalila Foundation
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References
The antioxidant paradox: less paradoxical now?
British Journal of Clinical Pharmacology · 2012 · 311 citations
Glutaminolysis and Transferrin Regulate Ferroptosis
Molecular Cell · 2015 · 1,981 citations
P-glycoprotein: from genomics to mechanism
Oncogene · 2003 · 1,054 citations
ROS Function in Redox Signaling and Oxidative Stress
Current Biology · 2014 · 6,564 citations
Evolution of the Cancer Stem Cell Model
Cell stem cell · 2014 · 2,215 citations
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