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BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

Annual Review of Biochemistry · 1993 · Vol. 62(1) · pp. 385–427

Michael M. Gottesman✉(National Institutes of Health)I Pastan

Abstract

The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More

Hippo pathway signaling and YAP/TAZDrosophila melanogasterRegulatorBiologyMultiple drug resistanceTransporterCell biologyMelanogasterHippo signaling pathwaySignal transductionGenetics

MeSH terms

AnimalsBiological TransportCarrier ProteinsDrug ResistanceHumansMembrane GlycoproteinsMutationGene Expression Regulation, NeoplasticATP Binding Cassette Transporter, Subfamily B, Member 1

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Multidrug efflux pumps of gram-negative bacteria