article Open AccessTop 1% cited
A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
Cell · 2006 · Vol. 125(2) · pp. 315–326
B Bernstein✉(Broad Institute)Tarjei S. Mikkelsen(Broad Institute)Xiaohui Xie(Broad Institute)Michael Kamal(Broad Institute)Dana J. Huebert(Massachusetts General Hospital)James Cuff(Broad Institute)Ben Fry(Broad Institute)Alex Meissner(Whitehead Institute for Biomedical Research)Marius Wernig(Whitehead Institute for Biomedical Research)Kathrin Plath(Whitehead Institute for Biomedical Research)Rudolf Jaenisch(Whitehead Institute for Biomedical Research)Alexandre Wagschal(Centre National de la Recherche Scientifique)Robert Feil(Centre National de la Recherche Scientifique)Stuart L. Schreiber(Howard Hughes Medical Institute)Eric S. Lander(Whitehead Institute for Biomedical Research)
Epigenetics and DNA MethylationGenomics and Chromatin DynamicsPluripotent Stem Cells ResearchBiologyChromatinBivalent (engine)Bivalent chromatinEpigeneticsDNA methylationHistoneGeneGeneticsEmbryonic stem cell
MeSH terms
Nanog Homeobox ProteinAnimalsCell DifferentiationCells, CulturedChromatinDNA-Binding ProteinsHistonesMaleMethylationMice, Inbred C57BLNucleic Acid ConformationStem CellsHomeodomain ProteinsGene Expression Regulation, DevelopmentalOligonucleotide Array Sequence Analysis
Funding
- Howard Hughes Medical Institute
- Massachusetts General Hospital
- Broad Institute
- European Science Foundation
- Boehringer Ingelheim Fonds
- National Institutes of Health
- National Cancer Institute
- National Institute of General Medical Sciences
- National Institute of Child Health and Human Development
Citations
5,379
FWCI
101.54
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References
61
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100%
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References
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