review Open AccessTop 1% cited
A decade of exploring the cancer epigenome — biological and translational implications
Nature reviews. Cancer · 2011 · Vol. 11(10) · pp. 726–734
Stephen B. Baylin✉(Sidney Kimmel Comprehensive Cancer Center)Peter A. Jones(University of Southern California)
Epigenetics and DNA MethylationCancer-related gene regulationHistone Deacetylase Inhibitors ResearchEpigenomeEpigeneticsBiologyDNA methylationChromatinComputational biologyEpigenomicsCancerGeneticsEpigenesis
MeSH terms
AnimalsHumansNeoplasmsGenomeEpigenesis, GeneticHistory, 20th CenturyHistory, 21st CenturyTranslational Research, BiomedicalEpigenomics
Funding
- Entertainment Industry Foundation
- National Institutes of Health
- National Cancer Institute
- National Institute of Environmental Health Sciences
Citations
2,835
FWCI
92.36
field-weighted impact
References
166
Percentile
100%
vs. same field & year
Citations per year
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References
The fundamental role of epigenetic events in cancer
Nature Reviews Genetics · 2002 · 5,646 citations
Inflammation and cancer
Nature · 2002 · 14,998 citations
A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
Cell · 2006 · 5,379 citations
Linking DNA methylation and histone modification: patterns and paradigms
Nature Reviews Genetics · 2009 · 2,272 citations
Hyperdynamic Plasticity of Chromatin Proteins in Pluripotent Embryonic Stem Cells
Developmental Cell · 2006 · 999 citations
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
Cancer Cell · 2006 · 1,324 citations
Chromatin signatures of pluripotent cell lines
Nature Cell Biology · 2006 · 1,338 citations
The epigenetic progenitor origin of human cancer
Nature Reviews Genetics · 2005 · 1,846 citations
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