reviewTop 1% cited
Cancer epigenomics: DNA methylomes and histone-modification maps
Nature Reviews Genetics · 2007 · Vol. 8(4) · pp. 286–298
Manel Esteller✉(Spanish National Cancer Research Centre)
Epigenetics and DNA MethylationRNA modifications and cancerGenomics and Chromatin DynamicsEpigenomicsBiologyEpigeneticsDNA methylationHistoneComputational biologyGeneticsCancer epigeneticsEpigenetics of physical exerciseCpG site
MeSH terms
DNA, NeoplasmGenetic TechniquesHistonesHumansNeoplasmsPharmacogeneticsPrognosisPromoter Regions, GeneticProtein BiosynthesisBiomarkers, TumorCpG IslandsDNA MethylationGene SilencingEpigenesis, Genetic
Citations
2,173
FWCI
64.07
field-weighted impact
References
106
Percentile
100%
vs. same field & year
Citations per year
Cited by
Current and Future Development in Lung Cancer Diagnosis
International Journal of Molecular Sciences · 2021 · 906 citations
Development of the pan-DAC inhibitor panobinostat (LBH589): Successes and challenges
Cancer Letters · 2009 · 414 citations
Epigenetic gene silencing in cancer: the DNA hypermethylome
Human Molecular Genetics · 2007 · 715 citations
Epigenetic modifications and human disease
Nature Biotechnology · 2010 · 2,844 citations
Causes and consequences of microRNA dysregulation in cancer
Nature Reviews Genetics · 2009 · 3,006 citations
Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine
International Journal of Cancer · 2008 · 939 citations
CpG islands – ‘A rough guide’
FEBS Letters · 2009 · 883 citations
Hallmarks of Cancer: The Next Generation
Cell · 2011 · 65,668 citations
References
Fingerprinting genomes using PCR with arbitrary primers
Nucleic Acids Research · 1990 · 5,215 citations
A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
Cell · 2006 · 5,379 citations
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.
Proceedings of the National Academy of Sciences · 1996 · 5,649 citations
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
Cancer Cell · 2006 · 1,324 citations
Chromatin signatures of pluripotent cell lines
Nature Cell Biology · 2006 · 1,338 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
The history of cancer epigenetics
Nature reviews. Cancer · 2004 · 2,348 citations
<i>MGMT</i> Gene Silencing and Benefit from Temozolomide in Glioblastoma
New England Journal of Medicine · 2005 · 7,163 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.