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Bert Vogelstein

Johns Hopkins UniversityORCID https://orcid.org/0000-0003-0766-3854
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Top Publications

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
Analytical Biochemistry198325,153 citations
A genetic model for colorectal tumorigenesis
Cell199012,052 citations
PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
New England Journal of Medicine20159,308 citations
p53 Mutations in Human Cancers
Science19918,098 citations
Cancer Genome Landscapes
Science20137,937 citationsFirst authorCorresponding
Genetic Alterations during Colorectal-Tumor Development
New England Journal of Medicine19886,737 citationsFirst authorCorresponding
Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies
Science Translational Medicine20145,005 citations
Lessons from Hereditary Colorectal Cancer
Cell19964,911 citations
Cancer genes and the pathways they control
Nature Medicine20044,243 citationsFirst authorCorresponding
Circulating mutant DNA to assess tumor dynamics
Nature Medicine20082,677 citations
The multistep nature of cancer
Trends in Genetics19931,857 citationsFirst authorCorresponding
Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer
Science Translational Medicine20161,429 citationsCorresponding
PUMA Induces the Rapid Apoptosis of Colorectal Cancer Cells
Molecular Cell20011,277 citationsCorresponding
Purification of DNA from formaldehyde fixed and paraffin embedded human tissue
Biochemical and Biophysical Research Communications1985810 citationsCorresponding
Recurrent <i>GNAS</i> Mutations Define an Unexpected Pathway for Pancreatic Cyst Development
Science Translational Medicine2011771 citations
Evolutionary dynamics of cancer in response to targeted combination therapy
eLife2013641 citations
Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway
PLoS Genetics2012630 citations
Frequent <i>ATRX</i> , <i>CIC</i> , <i>FUBP1</i> and <i>IDH1</i> mutations refine the classification of malignant gliomas
Oncotarget2012577 citations
An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms
The Journal of Pathology1994520 citations