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William R. Markesbery

University of Kentucky

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Publications

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Citations

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Impact (2-yr)

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Top Publications

Oxidative Stress Hypothesis in Alzheimer's Disease

Free Radical Biology and Medicine19972,368 citationsFirst authorCorresponding

Copper, iron and zinc in Alzheimer's disease senile plaques

Journal of the Neurological Sciences19982,096 citations

Impaired Proteasome Function in Alzheimer's Disease

Journal of Neurochemistry2000833 citations

Brain Regional Correspondence Between Alzheimer's Disease Histopathology and Biomarkers of Protein Oxidation

Journal of Neurochemistry1995776 citations

A Role for 4‐Hydroxynonenal, an Aldehydic Product of Lipid Peroxidation, in Disruption of Ion Homeostasis and Neuronal Death Induced by Amyloid β‐Peptide

Journal of Neurochemistry1997775 citations

Four-Hydroxynonenal, a Product of Lipid Peroxidation, is Increased in the Brain in Alzheimer’s Disease

Neurobiology of Aging1998677 citationsFirst authorCorresponding

Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease

Neurobiology of Aging2009653 citations

Changes in thiol content and expression of glutathione redox system genes in the hippocampus and cerebellum in Alzheimer's disease

Neuroscience Letters2001649 citations

Neurotrophic Factors Attenuate Glutamate‐Induced Accumulation of Peroxides, Elevation of Intracellular Ca<sup>2+</sup> Concentration, and Neurotoxicity and Increase Antioxidant Enzyme Activities in Hippocampal Neurons

Journal of Neurochemistry1995616 citations

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase‐related protein 2, α‐enolase and heat shock cognate 71

Journal of Neurochemistry2002582 citations

Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: possible relation to oxidative stress

Journal of the Neurological Sciences1996537 citationsCorresponding

Midlife blood pressure and neuritic plaques, neurofibrillary tangles, and brain weight at death: the HAAS☆

Neurobiology of Aging2000463 citations

Acrolein is increased in Alzheimer’s disease brain and is toxic to primary hippocampal cultures

Neurobiology of Aging2001445 citationsCorresponding

Low sensitivity in clinical diagnoses of dementia with Lewy bodies

Journal of Neurology2009277 citations