A critical review on pharmacognostical, phytochemical standardization and pharmacological evaluation of clerodendrum infortunatum

Abstract

In the rural areas of North India, clerodin, an active bitter substance found in Clerodendrum infortunatum Linn. (Verbenaceae), is a common and significant medicinal plant that is used as an anthelmintic and tonic. The plant requires careful research to determine its specific medicinal activity, even though it is used in Ayurveda, Unani medicine, and homeopathy in a variety of ways to treat conditions like diarrhea, skin disorders, venereal and scrofulous complaints, wounds, postpartum complications, as a vermifuge, laxative, and cholagogue, to remove ascarids from the anus, as external applications on tumors, etc. The reason leaves and roots are applied externally to tumors is because they contain clerodolone, clerodol, and a sterol that is now known as clerosterol. Extract from leaves and roots can be used to newly opened wounds. Because of the leaf extract, the percentage of hemoglobin rose. Patients who receive leaf extract treatment experience significant relief. In diabetic patients, the percentage of sugar decreased within twelve hours, applying edible oil and slightly heated leaves to the sore area of the body provides significant alleviation. The root extract was also used to identify seven sugars: fructose, glactose, lactose, maltose, sucrose, and raffinose. The hanging drop method was used to evaluate the vitality of the pollen. Fruit and seed set were used to measure reproductive success.