review Open AccessTop 1% cited
Epithelial-Mesenchymal Plasticity in Cancer Progression and Metastasis
Developmental Cell · 2019 · Vol. 49(3) · pp. 361–374
Wei Lu✉(Princeton University)Yibin Kang(Princeton University)
Cancer Cells and MetastasisMetastasis and carcinoma case studiesSarcoma Diagnosis and TreatmentBiologyMetastasisMesenchymal stem cellCancerCancer researchPlasticityCancer metastasisCell biologyGenetics
MeSH terms
Cell PlasticityAnimalsCell Transformation, NeoplasticFibroblastsHumansNeoplasm InvasivenessNeoplasm MetastasisNeoplasmsNeovascularization, PathologicNeoplastic Stem CellsEmbryonic DevelopmentEpithelial-Mesenchymal Transition
Funding
- U.S. Department of Defense
- Foundation for the National Institutes of Health
- Susan G. Komen for the Cure
- Breast Cancer Research Foundation
- Brewster Foundation
- Susan G. Komen
- National Institutes of Health
Citations
1,029
FWCI
57.22
field-weighted impact
References
150
Percentile
100%
vs. same field & year
Citations per year
Cited by
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References
Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis
Frontiers in Oncology · 2015 · 688 citations
Molecular mechanisms of epithelial–mesenchymal transition
Nature Reviews Molecular Cell Biology · 2014 · 8,050 citations
Snail and Slug Mediate Radioresistance and Chemoresistance by Antagonizing p53-Mediated Apoptosis and Acquiring a Stem-Like Phenotype in Ovarian Cancer Cells
Stem Cells · 2009 · 649 citations
An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530)
Cell Death and Disease · 2013 · 467 citations
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
Nature Cell Biology · 2008 · 3,861 citations
Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition
PLoS ONE · 2008 · 1,613 citations
Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transition
Nature Cell Biology · 2004 · 1,569 citations
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
Cell · 2008 · 8,672 citations
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