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The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

Cell · 2008 · Vol. 133(4) · pp. 704–715

Sendurai A. Mani✉(Whitehead Institute for Biomedical Research)Wenjun Guo(Whitehead Institute for Biomedical Research)Mai-Jing Liao(Whitehead Institute for Biomedical Research)Elinor Ng Eaton(Whitehead Institute for Biomedical Research)Ayyakkannu Ayyanan(École Polytechnique Fédérale de Lausanne)Alicia Y. Zhou(Whitehead Institute for Biomedical Research)Mary W. Brooks(Whitehead Institute for Biomedical Research)Ferenc Reinhard(Whitehead Institute for Biomedical Research)Cheng Zhang(Whitehead Institute for Biomedical Research)Michail Shipitsin(Dana-Farber Cancer Institute)Lauren L. Campbell(Dana-Farber Cancer Institute)Kornélia Polyák(Harvard University)Cathrin Brisken(École Polytechnique Fédérale de Lausanne)Jing Yang(University of California, San Diego)Robert A. Weinberg✉(Massachusetts Institute of Technology)

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Cancer Cells and Metastasis Digestive system and related healthBiologyEpithelial–mesenchymal transitionStem cellMesenchymal stem cellCancer stem cellEpitheliumCell biologyMetastasisCancer researchCell

MeSH terms

AnimalsCell Transformation, NeoplasticCells, CulturedEpithelial CellsHumansMammary Glands, AnimalMesodermStem CellsTumor Cells, CulturedNeoplastic Stem CellsSpheroids, CellularHyaluronan ReceptorsMammary Glands, HumanMiceCD24 Antigen

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