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iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data

BMC Bioinformatics · 2018 · Vol. 19(1) · pp. 534–534
Xijin GeEun SonRunan Yao

Abstract

Combining comprehensive analytic functionalities with massive annotation databases, iDEP ( http://ge-lab.org/idep/ ) enables biologists to easily translate transcriptomic and proteomic data into actionable insights.

Cancer-related molecular mechanisms researchRNA modifications and cancerMolecular Biology Techniques and ApplicationsBioconductorRNA-SeqComputational biologyTranscriptomeBiologymicroRNAKEGGComputer scienceGeneGene expression

MeSH terms

Homeobox A1 ProteinAnimalsB-LymphocytesCells, CulturedFibroblastsGene Expression RegulationHumansLungSoftwareTranscription FactorsTumor Suppressor Protein p53Sequence Analysis, RNAHomeodomain ProteinsComputational BiologyGene Expression Profiling

Funding

  • National Science Foundation
  • National Institutes of Health
  • National Institute of General Medical Sciences
  • Office of Experimental Program to Stimulate Competitive Research
Citations
1,671
FWCI
24.62
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150
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100%
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References
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BMC Bioinformatics · 2008 · 28,332 citations
GenePattern 2.0
Nature Genetics · 2006 · 2,105 citations
The Reactome pathway Knowledgebase
Nucleic Acids Research · 2015 · 6,002 citations
GAGE: generally applicable gene set enrichment for pathway analysis
BMC Bioinformatics · 2009 · 1,390 citations
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