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Learned Primal-Dual Reconstruction

IEEE Transactions on Medical Imaging · 2018 · Vol. 37(6) · pp. 1322–1332
Jonas AdlerOzan Oktem

Abstract

We propose the Learned Primal-Dual algorithm for tomographic reconstruction. The algorithm accounts for a (possibly non-linear) forward operator in a deep neural network by unrolling a proximal primal-dual optimization method, but where the proximal operators have been replaced with convolutional neural networks. The algorithm is trained end-to-end, working directly from raw measured data and it does not depend on any initial reconstruction such as filtered back-projection (FBP). We compare performance of the proposed method on low dose computed tomography reconstruction against FBP, total variation (TV), and deep learning based post-processing of FBP. For the Shepp-Logan phantom we obtain >6 dB peak signal to noise ratio improvement against all compared methods. For human phantoms the corresponding improvement is 6.6 dB over TV and 2.2 dB over learned post-processing along with a substantial improvement in the structural similarity index. Finally, our algorithm involves only ten forward-back-projection computations, making the method feasible for time critical clinical applications.

Medical Imaging Techniques and ApplicationsAdvanced Radiotherapy TechniquesDigital Radiography and Breast ImagingIterative reconstructionImaging phantomConvolutional neural networkDeep learningSignal-to-noise ratio (imaging)Artificial neural networkNoise (video)Similarity (geometry)Iterative method

MeSH terms

Deep LearningAlgorithmsHumansRadiographic Image EnhancementTomography, X-Ray ComputedPhantoms, Imaging
Citations
692
FWCI
47.40
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25
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100%
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