review Open AccessTop 1% cited

ChIP–seq: advantages and challenges of a maturing technology

Nature Reviews Genetics · 2009 · Vol. 10(10) · pp. 669–680

Peter J. Park✉(Harvard University)

Genomics and Chromatin Dynamics Single-cell and spatial transcriptomics Epigenetics and DNA MethylationBiologyChromatin immunoprecipitationComputational biologyDNA sequencingHistoneEpigeneticsProfiling (computer programming)ChipChromatinNucleosome

MeSH terms

AnimalsDNA-Binding ProteinsHumansNucleosomesSequence Analysis, DNAComputational BiologyEpigenesis, GeneticChromatin Immunoprecipitation

Funding

National Institutes of Health

Citations

2,264

FWCI

61.71

field-weighted impact

References

104

Percentile

100%

vs. same field & year

Citations per year

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References

Statistical significance for genomewide studies

Proceedings of the National Academy of Sciences · 2003 · 10,009 citations

A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells

Cell · 2006 · 5,379 citations

High-Resolution Profiling of Histone Methylations in the Human Genome

Cell · 2007 · 6,869 citations

The potential and challenges of nanopore sequencing

Nature Biotechnology · 2008 · 2,507 citations

Next-generation DNA sequencing

Nature Biotechnology · 2008 · 4,469 citations

Combinatorial patterns of histone acetylations and methylations in the human genome

Nature Genetics · 2008 · 2,322 citations

Database resources of the National Center for Biotechnology Information: update

Nucleic Acids Research · 2003 · 11,003 citations

Gene Ontology: tool for the unification of biology

Nature Genetics · 2000 · 43,975 citations

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