reviewTop 1% cited

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

Trends in Pharmacological Sciences · 2008 · Vol. 30(2) · pp. 85–94

Bharat B. Aggarwal✉(The University of Texas MD Anderson Cancer Center)Bokyung Sung(The University of Texas MD Anderson Cancer Center)

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Curcumin's Biomedical Applications Retinoids in leukemia and cellular processes Natural product bioactivities and synthesisCurcuminPharmacologyIn vivoInflammationCyclooxygenaseTumor necrosis factor alphaMedicineInterleukinImmunologyCytokine

MeSH terms

AnimalsAnti-Inflammatory Agents, Non-SteroidalAntioxidantsChronic DiseaseCurcuminHumansInflammationPhytotherapyDrug Delivery SystemsSpicesCurcuma

Citations

1,107

FWCI

19.19

field-weighted impact

References

132

Percentile

100%

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Citations per year

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References

Curcumin as “Curecumin”: From kitchen to clinic

Biochemical Pharmacology · 2007 · 2,184 citations

Curcumin (Diferuloylmethane) Down-Regulates Expression of Cell Proliferation and Antiapoptotic and Metastatic Gene Products through Suppression of IκBα Kinase and Akt Activation

Molecular Pharmacology · 2005 · 528 citations

Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl

Carcinogenesis · 2002 · 429 citations

Curcumin Therapy in Inflammatory Bowel Disease: A Pilot Study

Digestive Diseases and Sciences · 2005 · 428 citations

Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism

Carcinogenesis · 2007 · 672 citations

Modulation of arachidonic acid metabolism by curcumin and related -diketone derivatives: effects on cytosolic phospholipase A2, cyclooxygenases and 5-lipoxygenase

Carcinogenesis · 2004 · 428 citations

Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer

Clinical Cancer Research · 2008 · 1,303 citations

Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo

Journal of Biological Chemistry · 2004 · 2,288 citations

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