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Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer

Clinical Cancer Research · 2008 · Vol. 14(14) · pp. 4491–4499

Navneet K. Dhillon✉(Advanced Cancer Therapeutics)Bharat B. AggarwalRobert A. NewmanRobert A. WolffAjaikumar B. KunnumakkaraJames L. AbbruzzeseChaan S. Ng(The University of Texas MD Anderson Cancer Center)Vladimir Badmaev(Sabin Vaccine Institute)Razelle Kurzrock(Advanced Cancer Therapeutics)

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Abstract

Oral curcumin is well tolerated and, despite its limited absorption, has biological activity in some patients with pancreatic cancer.

Curcumin's Biomedical Applications Retinoids in leukemia and cellular processes NF-κB Signaling PathwaysCurcuminMedicinePancreatic cancerCytokinePeripheral blood mononuclear cellPharmacologyGemcitabinePancreatic diseaseInternal medicineCancer

MeSH terms

Electrophoretic Mobility Shift AssayAdenocarcinomaAdultAgedAntineoplastic AgentsCurcuminFemaleHumansImmunohistochemistryMaleMiddle AgedPancreatic NeoplasmsCytokinesNF-kappa BCyclooxygenase 2

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Clinical Cancer Research · 2004 · 1,233 citations

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