article Open AccessTop 1% cited
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
Cell · 2006 · Vol. 126(6) · pp. 1121–1133
Ivaylo I. Ivanov(New York University)Brent S. McKenzieLiang Zhou(New York University)Carlos E. Tadokoro(New York University)Alice Lepelley(New York University)Juan J. Lafaille(New York University)J. Daniel✉Dan R. Littman✉(Howard Hughes Medical Institute)
Psoriasis: Treatment and PathogenesisIL-33, ST2, and ILC PathwaysWhipple's Disease and InterleukinsRAR-related orphan receptor gammaBiologyOrphan receptorInnate lymphoid cellProinflammatory cytokineInterleukin 17Cell biologyTranscription factorImmunologyNuclear receptor
MeSH terms
AnimalsAutoimmune DiseasesCell DifferentiationDisease Models, AnimalT-Lymphocytes, Helper-InducerHematopoietic Stem CellsHomeostasisIntestinal MucosaMice, Inbred BALB CMice, Inbred C57BLReceptors, Thyroid HormoneCD4 AntigensInterleukin-6Receptors, Retinoic AcidMice, Knockout
Funding
- Howard Hughes Medical Institute
- Chongqing University of Arts and Sciences
Citations
5,064
FWCI
82.87
field-weighted impact
References
59
Percentile
100%
vs. same field & year
Citations per year
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References
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Nature Immunology · 2001 · 2,508 citations
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Nature Immunology · 2005 · 4,203 citations
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The Journal of Experimental Medicine · 2005 · 4,029 citations
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Interleukin-17 Family Members and Inflammation
Immunity · 2004 · 2,349 citations
Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12
Immunity · 2000 · 2,788 citations
Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
Nature Immunology · 2005 · 4,662 citations
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