review Open AccessTop 1% cited
Sex Differences in the Expression of Hepatic Drug Metabolizing Enzymes
Molecular Pharmacology · 2009 · Vol. 76(2) · pp. 215–228
David J. Waxman✉(Boston University)Minita G. Holloway(Boston University)
Pharmacogenetics and Drug MetabolismHormonal Regulation and HypertensionEstrogen and related hormone effectsEnzymeDrug metabolismDrugLiver enzymeBiologyBiochemistryChemistryPharmacologyEndocrinology
MeSH terms
AnimalsFemaleGene Expression RegulationHumansLiverMaleModels, BiologicalSex Characteristics
Funding
- National Institutes of Health
- National Institute of Diabetes and Digestive and Kidney Diseases
Citations
807
FWCI
47.01
field-weighted impact
References
209
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100%
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References
The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes
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Archives of Biochemistry and Biophysics · 1999 · 762 citations
Evidence for an Endogenous Ultradian Rhythm Governing Growth Hormone Secretion in the Rat
Endocrinology · 1976 · 742 citations
Growth Hormone Regulation of Sex-Dependent Liver Gene Expression
Molecular Endocrinology · 2006 · 451 citations
Hepatocyte Nuclear Factor 4α (Nuclear Receptor 2A1) Is Essential for Maintenance of Hepatic Gene Expression and Lipid Homeostasis
Molecular and Cellular Biology · 2001 · 1,120 citations
Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future
Trends in Pharmacological Sciences · 2004 · 669 citations
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