article Open AccessTop 10% cited
A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas
Leukemia · 2008 · Vol. 22(5) · pp. 1026–1034
Sriram Balasubramanian✉(Pharmacyclics (United States))Jason Ramos(Pharmacyclics (United States))Weigang Luo(Pharmacyclics (United States))Mint Sirisawad(Pharmacyclics (United States))Erik Verner(Pharmacyclics (United States))Joseph J. Buggy(Pharmacyclics (United States))
Histone Deacetylase Inhibitors ResearchPeptidase Inhibition and AnalysisUbiquitin and proteasome pathwaysThapsigarginJurkat cellsApoptosisCell biologyHistone deacetylaseCancer researchHistone deacetylase inhibitorBiologyEndoplasmic reticulumChemistry
MeSH terms
CalciumHistone DeacetylasesHumansHydroxamic AcidsIndolesRepressor ProteinsLymphoma, T-CellApoptosisCell Line, TumorPhospholipase C gammaHistone Deacetylase Inhibitors
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Molecular Cell · 2006 · 1,476 citations
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Oncogene · 2007 · 1,533 citations
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Trends in Pharmacological Sciences · 1998 · 596 citations
Histone deacetylases (HDACs): characterization of the classical HDAC family
Biochemical Journal · 2003 · 3,077 citations
Class II histone deacetylases: versatile regulators
Trends in Genetics · 2003 · 655 citations
Receptor-coupled signal transduction in human polymorphonuclear neutrophils: effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness.
Journal of Pharmacology and Experimental Therapeutics · 1990 · 572 citations
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