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ATM and related protein kinases: safeguarding genome integrity

Nature reviews. Cancer · 2003 · Vol. 3(3) · pp. 155–168
Yosef Shiloh
DNA Repair MechanismsCancer-related Molecular PathwaysCarcinogens and Genotoxicity AssessmentDNA damageGenome instabilityAtaxia-telangiectasiaBiologyKinaseDNA repairSignal transductionGenomeCell biologyCancer

MeSH terms

AnimalsAtaxia TelangiectasiaCell Transformation, NeoplasticDNA DamageDNA RepairDNA-Binding ProteinsEnzyme ActivationMultigene FamilyHumansModels, GeneticNeoplastic Syndromes, HereditarySignal TransductionProtein Serine-Threonine KinasesMice, KnockoutCell Cycle Proteins
Citations
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References
Regulation and function of the p53 tumor suppressor protein
Current Opinion in Cell Biology · 2001 · 722 citations
Cell cycle checkpoint signaling through the ATM and ATR kinases
Genes & Development · 2001 · 1,958 citations
Sensing and repairing DNA double-strand breaks
Carcinogenesis · 2002 · 1,130 citations
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