reviewTop 1% cited
Bcl-2-family proteins and the role of mitochondria in apoptosis
Current Opinion in Cell Biology · 2003 · Vol. 15(6) · pp. 691–699
Tomomi Kuwana✉(La Jolla Institute for Immunology)Donald D. Newmeyer(La Jolla Institute for Immunology)
Cell death mechanisms and regulationMitochondrial Function and PathologyAutophagy in Disease and TherapyIntermembrane spaceMitochondrial intermembrane spaceCell biologyBiologyBcl-2 familyMitochondrionEndoplasmic reticulumApoptosomeMitochondrial apoptosis-induced channelTranslocase of the inner membrane
MeSH terms
AnimalsCalciumEndoplasmic ReticulumHumansMembrane PotentialsMitochondriaPermeabilitySignal TransductionApoptosisProtein Structure, TertiaryProto-Oncogene Proteins c-bcl-2
Citations
628
FWCI
12.64
field-weighted impact
References
94
Percentile
99%
vs. same field & year
Citations per year
Cited by
Cellular response to endoplasmic reticulum stress: a matter of life or death
Cell Death and Differentiation · 2006 · 682 citations
Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario
Cell Death and Differentiation · 2006 · 605 citations
References
The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet
Cell Death and Differentiation · 2002 · 666 citations
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
Cancer Cell · 2002 · 1,634 citations
PUMA, a Novel Proapoptotic Gene, Is Induced by p53
Molecular Cell · 2001 · 2,283 citations
A Distinct Pathway Remodels Mitochondrial Cristae and Mobilizes Cytochrome c during Apoptosis
Developmental Cell · 2002 · 1,065 citations
The Combined Functions of Proapoptotic Bcl-2 Family Members Bak and Bax Are Essential for Normal Development of Multiple Tissues
Molecular Cell · 2000 · 1,468 citations
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
Cell · 1998 · 4,423 citations
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
The EMBO Journal · 1998 · 1,231 citations
PUMA Induces the Rapid Apoptosis of Colorectal Cancer Cells
Molecular Cell · 2001 · 1,277 citations
Related articles
Bcl-2-family proteins and the role of mitochondria in apoptosis
Current Opinion in Cell Biology · 2003 · 628 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.